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[Doctor][해외] Doctors Best Vitamin D3 -- 2000 IU - 180 Softgel Capsules

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Seller Information
Seller Information
Seller NewYork Mania
Seller's Address
  • Ship-From Address

    NJ , SUITE 6 Clifton

  • Return/Exchange Address

    S HACKENSACK, NJ

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Basic Information of Product

Basic Information of Product
Product Status/Sales Type New Product No. 1384518
Weight (kg) 1 kg Country of Origin N/A
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GST Applicable Not Applicable (Non-GST seller)
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Product Name
[해외] Doctors Best Vitamin D3 -- 2000 IU - 180 Softgel Capsules
Product Code: PROD1540007390
Product Information

Doctor**s Best Vitamin D3 Description Science-Based Nutrition™2000 IU Vitamin D3 per ServingSupports Healthy Immune System, Heart, & Bone Health
Vitamin D3 (cholecalciferol) is a nutrient that is critical to many bodily functions. Vitamin D3 is beneficial for supporting bone health, immune wellness, cardio- vascular function, and cellular metabolism, among others. Mounting research is highlighting the ever-increasing benefits of optimal vitamin D3 status. Vitamin D3 is known to interact with over 200 different genes and thus plays a crucial regulatory role as a metabolic activator for a multitude of metabolic processes.
Vitamin D from dietary intake or sun exposure requires two activation steps in the body. The first activation occurs in the liver, while the second activation occurs in the kidneys, allowing for regulation of calcium metabolism. However, vitamin D receptors are present throughout the body, in tissue such as the skin, cartilage, heart, prostate, bones and intestines. Thus, the second activation step also takes place in local tissues. Recent discoveries have highlighted the important modulatory effects of vitamin D on various cells of the immune system.
Vitamin D enhances and regulates immune function
Studies show that vitamin D has important immunomodulatory effects. It is known that various cells of the immune system, such as T lymphocytes and antigen presenting cells, express the vitamin D receptor on their surface when activated. Recently, it has been found that treatment of these immune cells with vitamin D influences their expression of cytokines, which are chemical messengers of the immune system. The immune modulating effects of vitamin D extend to monocytes and dendritic cells of the immune system as well. Dendritic cells are important antigen-processing cells of the immune system that function to initiate the immune response. By altering the cytokine expression of dendritic cells, vitamin D may prevent overactivity of the immune response and keep the immune system in a normal healthy state of vigilance.
Vitamin D supports optimal cardiovascular function
Research has uncovered the role vitamin D plays in supporting cardiac function. Heart myocytes (cells) express the vitamin D receptor, as do smooth muscle cells of blood vessels. The benefits of vitamin D on the heart are potentially far-reaching. Studies on mice heart cells have shown that vitamin D administration impacts their growth and proliferation. In these cells, vitamin D inhibited the release of a protein that could be detrimental to the function of these cells, displaying cardioprotective properties. It has also been shown that vitamin D has a modulatory effect on heart rhythm. Again, in mouse heart cells, knocking out the effects of the vitamin D receptors led to an increased rate of contraction and relaxation. In normal mouse cardiac myocytes, administration of vitamin D led to normalization of heart contractility. Further studies in mice have led researchers to conclude that vitamin D supports the overall structure and function of the heart in terms of shape, size and performance.
Studies in humans have confirmed the importance of vitamin D for heart function. In a study consisting of 1,739 participants from the Framingham Offspring Study, those individuals with the highest levels of vitamin D had superior cardiac function in relation to those with low vitamin D levels. These results make sense when taken in context of the overall effects of low vitamin D. These effects include an imbalance in the immune production of inflammatory markers, disturbing the normal inflammatory response and leading to potential effects on all tissues, including the heart and blood vessels. Restoration of optimal vitamin D status supports a healthy, normal inflammatory response and may thus restore the optimal health of the heart and cardiovascular system.
Furthermore, recent research highlights the profound benefits of vitamin D sufficiency in the realm of markers of cardiovascular wellness. Studies have previously shown that vitamin D supplementation has no effect on weight loss. However a recent study conducted in 200 healthy overweight individuals has shown that vitamin D supplementation can enhance the cardiovascular benefits associated with weight loss. The individuals participating in a 12-month weight reduction program were divided into two groups ? one received placebo while the other group received suppl
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Seller Information

Seller Information
Seller NewYork Mania
Ship-From Address NJ , SUITE 6 Clifton
Return/Exchange Address S HACKENSACK, NJ
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Return / Exchange Policy

  1. Cancellation
    • Request for cancellation if product has not been dispatched after payment completion.
  2. Return
    • Request for return within 7 calendar days following delivery date.
    • Check seller’s approval on buyer’s request.
    • Buyer sends product in question to seller.
    • Seller receives and checks returned product
    • Seller approves return and return is completed.
  3. Exchange
    • Request for exchange within 7 calendar days following receipt of delivery.
    • Check seller’s approval on buyer’s request.
    • Buyer sends product in question to seller.
    • Seller receives and checks returned product
    • Seller send new product to buyer, and buyer receives it, and exchange is completed.
  • How to Request for Cancellation/Return/Exchange
    • You can request for cancellation after completing payment and if product has not been dispatched by then, cancellation request is approved and you can receive refund.
      But, in case seller has already dispatched product, cancellation request can be rejected.
    • You can request for return after obtaining product, you should send the product in question to seller.
      After seller checks if returned product is flawed, and approves your request, return is completed and payment is refunded.
    • You can request for exchange if wrong product is shipped, you should send the product in question to seller.
      After seller checks if returned product is flawed, seller approves your request, and re-sends new product.
  • Criteria for Return/Exchange

    You can request for return/exchange within 7 calendar days following delivery date. But return/exchange request cannot be made in following cases:

    • When request due to change of mind is made after 7 calendar days following delivery date
    • When product is used, destroyed or damaged
    • When tag attached to product is removed or package of product is opened and product value is damaged
    • When sealed package is opened or packaging materials are lost
    • When too much time has passed and product value has so decreased that its re-sale is not possible
    • When return/exchange request is made for customized product such as hand-made shoes or accessories
    • When components of product (including free gift) have been used or lost
    • When buyer did not follow instructions included in product
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